Isotopically Labeled Compounds
Medchemexpress LLC (S)-Cystathionine-d4 | 61949-06-2 | 97.1% | 226.29 | 5 MG
(S)-Cystathionine-d4 is the deuterium labeled (S)-Cystathionine. It is for research use only and not sold to patients. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Sigma Aldrich Fine Chemicals Biosciences TAURINE-1,1,2,2-D4-100MG
Taurine-1,1,2,2-d4, 100MG, MOLWT: 129.17, MFCD01311693
Medchemexpress LLC Azelaic acid-d14 | 119176-67-9 | 99.86% | 5 MG
Azelaic acid-d14 is the deuterium labeled Azelaic acid. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; it is also a component of a number of hair and skin conditioners. It is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Acetylcholine-d4 chloride | 344298-94-8 | 99.21% | 5 MG
Acetylcholine-d4 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride) is a neurotransmitter, a potent and BBB-permeable cholinergic agonist, and a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). It also inhibits p53 mutant peptide aggregation in vitro.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes have potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Glipizide-d11 | 1189426-07-0 | MFCD08705009 | 96.4% | 1 MG
Glipizide-d11 is the deuterium-labeled form of Glipizide, a potent, orally active sulfonylurea class anti-diabetic agent. It is primarily used in type 2 diabetes mellitus research, and not for type 1. This compound acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans.
- Deuterium labeled Glipizide
- Potent and orally active
- Used in type 2 diabetes mellitus research
- Acts on ATP-sensitive potassium (KATP) channels
- Can be used as a tracer for quantitative analysis
- Suitable as an internal standard for quantitative analysis
Medchemexpress LLC Fexofenadine-d6 | 548783-71-7 | 99.3% | 1 MG
Fexofenadine-d6 (MDL-16455-d6) is a deuterium-labeled form of Fexofenadine, which acts as an antihistamine pharmaceutical agent. This compound is intended for research use only. It can be utilized as a tracer and as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS. Deuteration, the incorporation of stable heavy isotopes into drug molecules, is used for quantitation during drug development and has shown potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Vericiguat-d3 hydrochloride | 1350653-20-1 | 99.8% | 465.86 | 1 MG
Vericiguat-d3 (BAY1021189-d3) hydrochloride is a deuterated Vericiguat with tracer functionality. Vericiguat is an orally available stimulator of guanylate cyclase.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Apalutamide-13C,d3 | 956104-40-8 | 99.9% | 481.45 | 500 UG
Apalutamide-13C,d3 is a 13C- and deuterium labeled Apalutamide, which is a potent and competitive androgen receptor antagonist. It is intended for research use only and serves as a valuable tool for quantitative analysis in drug development.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporated stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules for quantitation
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Adenine-13C | 86967-48-8 | 99.1% | 50 MG
Adenine-13C is the 13C labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases found in the nucleic acid of DNA. It serves as a chemical component of both DNA and RNA. Adenine also plays a significant role in biochemistry, specifically in cellular respiration, forming both ATP and cofactors like NAD and FAD, and in protein synthesis.
- Isotope labeled for use as a tracer.
- Can be used as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
Medchemexpress LLC Ethylenethiourea-d4 | 352431-28-8 | 106.18 | 1 MG
Ethylenethiourea-d4 is the deuterium labeled Ethylenethiourea. Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic, and it is orally active.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Acetamide-2,2,2-d3, N-(methyl-d3) | 3669-73-6 | MFCD01073934 | 98.6% | 79.13 g/mol | C3HD6NO | 1 MG
N-Methylacetamide-d6 is the deuterium-labeled analogue of N-methylacetamide provided as a high-purity stable isotope reagent for analytical and research applications. It is used as an internal standard and reference in mass spectrometry, NMR, and tracer studies.
- High isotopic purity for accurate quantitation and spectral referencing.
- Suitable as an internal standard for mass spectrometry analyses.
- Provides a deuterium-labeled reference for NMR experiments.
- Supplied in small, precise quantities for method development.
- Certificate of analysis and safety data sheet available.
- Molecular weight 79.13 g/mol, formula C3HD6NO.
Cayman Chemical Lyso-PAF C-16-d4 100ug
An internal standard for the quantification of PAF C-16 by GC- or LC-MS.
Cayman Chemical Sphingosine (d18:1), Purity: ≥98%, CAS: 123-78-4, 25 mg
Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits PKC and phosphatidic acid phosphohydrolase, whereas it activates PLD and DAG kinase. Phosphorylation of sphingosine by SPHK 1 and SPHK 2 produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.
Medchemexpress LLC Cariprazine-d6 | 1308278-67-2 | MFCD00038264 | 98.7% | 433.45 | C21H26D6Cl2N4O | 10 MG
Cariprazine-d6 is a deuterium-labeled analogue of the antipsychotic cariprazine provided as a characterized reference standard for research use. It contains six deuterium atoms and is intended for use as an internal standard or tracer in analytical, pharmacokinetic, and metabolite studies; supporting documentation includes a product data sheet and safety data sheet.
Cambridge Isotope Laboratories L-ALANINE (13C3, 99%; 15N, 99%), 0.1 G, 202407-38-3
L-ALANINE (13C3, 99%; 15N, 99%), 0.1 G, 202407-38-3